2007 International Mock Board Exam Coalition

Central Region	University of Texas
Southwestern Medical Center	03/04/2007	
Northeastern Region	Yale University
	03/24/2007	
Centers for Disease Control and Prevention	Center for Disease Control and Prevention, Atlanta, GA	04/13/2007	
Southeastern Region	North Carolina State University
	05/19/2007	
International
	Europe	06/02/2007	
Pacific Northwest Region	Oregon Health & Science University
and Portland VA Medical Center	06/09/2007	

Practical Section – 75 Questions
Referenced Answers

17 pages

Practical Exam Contributors
Cheryl Haughton, DVM, DACLAM - Central Region Coordinator
David Kurtz, DVM, PhD, DACLAM – Southeastern Region Coordinator
Stephanie Murphy, VMD, PhD, DACLAM - Pacific Northwest Region Coordinator
Peter Smith, DVM, DACLAM - Northeastern Region Coordinator
Mallory Tate, DVM – CDCP Coordinator
Mary Ann Vasbinder, DVM, DACLAM - Southeastern Region Coordinator
Scout Chou, VMD, DACLAM
Suzanne Craig, DVM, DACLAM
Sylvia Gografe, DVM, PhD, DACLAM
Angela King-Herbert, DVM, DACLAM
Ken Salleng, DVM

This examination is meant to be used as a study tool when preparing for the ACLAM Certifying Examination.  The material presented in this mock examination follows the role delineation document, but is not necessarily reflective of the ACLAM Certifying Examination.

There is one correct answer for each question.

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Etiology, etiologic agent, cause or causative agent:  Indicate only the agent, e.g., Mycobacterium tuberculosis or trauma

Etiologic diagnosis:  Indicate the causative agent and the site of the lesion, e.g., esophageal candidiasis

Morphological diagnosis:  Indicate the organ, the process and the distribution (if indicated), e.g., diffuse ulcerative colitis or uterine Adenocarcinoma.

Disease:  Indicate the common name for the condition, e.g., measles or slobbers

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1.	What is the function of the piece of equipment shown in the slide?

a.	Metabolic chair
b.	Restraint device
c.	Surgical device
d.	Supply storage
e.	Feeding device

2.	What is the genus and species of this rabbit parasite?

a.	Chyletiella parasitovorax
b.	Psoroptes cuniculi
c.	Listrophorus gibbus
d.	Sarcoptes scabiei
e.	Passalurus ambiguus

3.	What is the condition depicted in this slide?

a.	Genital wart
b.	Genital hernia
c.	Dystocia
d.	Rectal prolapse
e.	Prolapsed prepuce

4.	Which agent is likely to cause the condition in these slides?

a.	Swine pox
b.	Pediculosis
c.	Sarcoptes scabiei
d.	Dermatophytosis
e.	Herpesvirus

5.	Which type of suture material is most likely to cause this type of skin lesion in Xenopus laevis?

a.	Monofilament nylon
b.	Braided silk
c.	Polypropylene
d.	Polyglactin 910
e.	Polydioxanone

6.	During a surgical procedure the femoral artery of a rabbit was ligated to induce ischemia. What is the instrument in the lower part of the picture called to spread the incision?

a.	Senn Rake Retractor
b.	Weitlander Retractor
c.	Balfour Retractor
d.	Gelpi Retractor
e.	U.S. Army-Pattern Retractor

7.	What is the most likely name of the disease causing the condition depicted in these three pictures?

a.	Hydronephrosis
b.	Spontaneous chronic progressive nephrophathy
c.	Urinary calculi
d.	Proteus mirabilis
e.	Mouse urologic syndrome

8.	What is device depicted in this slide called?

a.	Skinner box
b.	Holtzman box
c.	Induction chamber
d.	Metabolic cage
e.	Barnes Maze

9.	What is the genetic designation for this immunodeficient mouse?

a.	hr-hairless
b.	hrrh-hairless rhino
c.	nu-nude
d.	nustr-nude streaker
e.	motheaten

10.	Which of the following organism is reported to contribute to this clinical condition seen in gerbils?

a.	Staphylococcus xylosus
b.	Staphylococcus intermedius
c.	Streptococcus pneumoniae
d.	Staphylococcus meriones
e.	Bordetella bronchiseptica

11.	Which is the method of choice to euthanize this species?

a.	Decapitation
b. 	Carbon dioxide asphyxiation
c. 	IV barbiturate
d. 	Electrocution
e.	Tricaine methane sulfonate in water 

12.	Unlike Old World primates, which of the following is an essential nutrient for this species?

a.	Vit. B6
b.	Vit. B12
c.	Vit. D3
d.	a and c
e.	none of the above

13.	According to the Animal Welfare Act, what group is this cetacean (Delphinus delphis) placed for minimum horizontal dimension (MHD)?

a.	I
b.	II
c.	III
d.	IV
e.	V

14.	This finding was detected in a pig at necropsy.  How should this finding be interpreted?

a.	Abnormal
b.	Only seen in this species
c.	Malignant tumors
d.	Sporadic incidental finding

15.	The 3-week to 4-month-old pigs shown in this slide presented for lameness, depression, neurological signs, and death.  Gross necropsy findings included polyarthritis, fibrinous pleuritis and pericarditis, and leptomeningitis.  Of this list, what is the most likely etiological agent?  

a.	Haemophilus parasuis
b.	Brachyspira hyodysenteriae
c.	Mycoplasma hyopneumoniae
d.	Wilsonia stevenicus
e.	Pasteurella multocida

16.	What is the most reliable characteristic distinguishing adult males from females of the genera shown in this slide?

a.	Anogenital distance
b.	Only the males produce alkaloid toxin
c.	The males are brightly colored, while the females are a dilute brown color
d.	In males, the tympanic membrane is twice the size of females
e.	The females are mute

17.	Upon necropsy of a recently acquired cynomolgus macaque the following lesion was noticed.  What is the etiology for this condition?

a.	Strongyloidosis
b.	Nochtia nochti
c.	Hydatid cyst
d.	Cysticercosis
e.	Pentastomes

18.	What is the use of this device in laboratory animal facilities?

a.	Air purification
b.	Sound attenuation
c.	Water purification
d.	Protein analysis
e.	Waste disposal

19.	When this animal is fed an arginine free diet and exposed to influenza and aspirin, what human disease is induced?  

a.	H5N1
b.	1812 Influenza virus
c.	Hypergammaglobulinemia
d.	Reyes syndrome
e.	Sjogren’s syndrome

20.	What is the genus of this animal?

a.	Mastromys
b.	Peromycus
c.	Mystromys
d.	Spermophilus
e.	Sigmodon

21.	What is this species a common model for?

a.  Adenovirus
b.  Plague
c.  Measles
d.  Leishmaniasis
e.  Herpesvirus

22.	This is a fluid percussion device, it is most commonly used to

a.	Test material hardness
b.	Drill bones
c.	Create dental anomalies
d.	Induce neurologic lesions
e.	Test auditory function

23.	This is an F/air canister.  The NIOSH maximum limit for personnel exposure to halogenated anesthetic gases is:

a.	2 ppm
b.	8 ppm
c.	20 ppm
d.	40 ppm
e.	60 ppm

24.	What is the important type of enrichment needed for this animal?

a.  Secluded areas
b.  Individual housing
c.  Dust baths
d.  Light box
e.  Whole body feeder

25.	What must be done to ensure the device functions well that the employee is wearing?

a.  Fit Testing
b.  Culturing
c.  Health screen
d.  Body wraps
e.  Body  acclimate

26.	What does the document depicted on this slide state with respect to training?

a.  Only animal care staff need be trained to work with animals.
b.  Technician staff may not train investigators in animal use.
c.  Investigators, techs, etc. must be trained to do animal techniques.
d.  Formal training is not necessary to work with animals.

27.	What is the genus and species of this parasite found in rodents?

a.	Syphacia muris
b.	Syphacia obvelata
c.	Rodentolepis nana
d.	Aspicularis tetraptera
e.	Hymenolepsis diminuta

28.	What is the purpose of the depicted apparatus?

a.	Feeding
b.	Port implantation
c.	Restraint
d.	Orthopedic repair

29.	What is the objective of AWIC?

a.  Provide an incident command in the case of animal emergencies 
b.  Report animal welfare concerns to the USDA
c.  A CDC directive to inform the public about Avian Influenza
d.  Provide information on animal welfare

30.	What is the advantage of the dual corridor system in animal facility design?

a.	Easy movement in the animal facility
b.	To decrease the potential for cross contamination 
c.	Optimized animal housing space
d.	Decreased cost of building the facility.

31.	What is the purpose of this apparatus?

a.	Communication
b.	Vascular access
c.	Electrical stimulation
d.	Surveillance

32.	The wound depicted in this slide was inflicted by the animal depicted in this slide.  What is the zoonotic pathogen of concern?

a.	Streptobacillus moniliformis
b.	Brucella bovis
c.	Toxoplasma gondii
d.	Bartonella henselae

33.	List the genus and species of the animal depicted in this slide:

a.  Chinchilla laniger
b.  Chinchilla chinchilla
c.  Oryctolagus cuniculus
d.  Mesocricetus auratus
e.  Cavia porcellus

34.	Name the most likely cause of the condition of these mice.

a.  Barbering
b.  Tail vein bleeding
c.  Fight / bite wounds
d.  Foot pad injections
e.  Ectromelia

35.	Identify the equipment depicted in this slide:

a.  Anesthesia machine
b.  Fluid pump
c.  Blood gas machine
d.  Cautery
e.  Blood pressure monitor

36.	Name the condition of this mouse.

a.  Scabby skin disease
b.  Scaly skin disease
c.  Mouse mange
d.  Skin slough
e.  Ulcerative dermatitis

37.	According to the Animal Welfare Act, what minimum age must this animal be to be transported in the same primary enclosure as adults, other than its dam?

a.  12 weeks
b.  6 months
c.  1 year
d.  4 months
e.  8 weeks

38.	According to the CDC, which Biosafety level(s) requires this type of containment?

a.  BSL-1
b.  BSL-1 & BSL-2
c.  BSL-3
d.  BSL-2 & BSL-3
e.  BSL-3 & BSL-4

39.	Name the device.

a.  Rodent microwave
b.  Sterotaxic device
c.  Glass bead sterilizer
d.  Instrument holder
e.  Micro autoclave

40.	What does this acronym stand for?

a.  Certified Mouse Animal Researcher
b.  Certified Murine Animal Researcher
c.  Certified Manager of Animal Resources
d.  Certified Manager of Animal Research
e.  Certified Manager of Laboratory Animal Resources

41.	The following level of lighting is recommended by the Guide:

a.	400 lux at 3 meters above the floor
b.	325 lux at 2 meters above the floor
c.	325 lux at 1 meter above the floor
d.	425 lux at 1 meter above the floor

42.	Which of the following drugs is recommended when malignant hyperthermia becomes an anesthetic complication?

a.	Fluids only
b.	Flunixin megalamine
c.	Dantrolene
d.	Pentobarbitol

43.	Which of the following best describes the reproductive characteristics of this species?

a.	Seasonal breeder, gestation of about 164 days, interbirth interval of 360 days
b.	Nonseasonal breeder, gestation of about 164 days, interbirth interval of 380 days
c.	Seasonal breeder, gestation of about 185 days, interbirth interval of 360 days
d.	Nonseasonal breeder, gestation of about 164 days, interbirth interval of 360 days
e.	Seasonal breeder, gestation of about 185 days, interbirth interval of 380 days

44.	If, in the opinion of the attending veterinarian, it is inappropriate for this species to exercise because of their health, condition, or well-being a research facility may be exempted from providing opportunities for such exercise. How frequently and by whom must these exemptions be reviewed

a.	Weekly by a designated husbandry staff member
b.	Weekly by a designated laboratory staff member
c.	Weekly by the attending veterinarian
d.	Every 30 days by a designated husbandry staff member
e.	Every 30 days by the attending veterinarian

45.	What animal model can be produced in this species by the administration of alloxan?

a.	Hyperthyroidism with hypertrophic cardiomyopathy
b.	Myasthenia gravis with megasophagus and facial nerve paralysis
c.	Huntington’s disease with severe dyskinesias
d.	Renal hypertension and intrarenal reflux
e.	Type 2 diabetes mellitus with severe coronary atherosclerosis

46.	The potential for the transmission of what organism, capable of causing high mortality in one of these species, is the primary reason that these two animal types should be housed separately

a.	Beilerincus rudolphus
b.	Bordetella bronchiseptica
c.	Chlamydophila psittaci
d.	Cytomegalovirus
e.	Pasteurella multocida

47.	In a colony of immuno-deficient strain of mice, suckling mice were noted to have watery diarrhea and mortality. The histology is presented on the slide. What is the most likely etiologic agent: 

a.	Citrobacter rodentium
b.	Clostridium piliforme
c.	Mouse parvovirus (MPV)
d.	Mouse Hepatitis Virus (MHV)
e.	Mouse Adenovirus (MAdV)

48.	This animal is used to model: 

a.	Cyclic hematopoiesis
b.	Muscular dystrophy
c.	Hypothyroidism
d.	Copper storage disease (Wilson’s disease)
e.	Beiler’s disease

49.	What ideal light level is recommended to house this species:

a.	125 lux
b.	325 lux
c.	525 lux
d.	800-1100 lux
e.	> 1400 lux

50.	The animal pictured is predisposed to which of the following congenital disorders

a.	Schistosomus reflexus 
b.	Sporadic exophthalmos
c.	Factor IX Deficiency
d.	Diaphragmatic Hernia
e.	Hirschsprung’s Disease

51.	The age of sexual maturation of the animal pictured is:

a.	4-6 months
b.	5-7 months
c.	6-8 months
d.	7-9 months
e.	8-10 months

52.	The goat in this image is undergoing what procedure?

a.	Dialysis
b.	Plasmapheresis
c.	Terminal exsanguination
d.	Whole blood transfusion
e.	Whole blood donation

53.	This kidney was removed from a 12-day-old puppy that died acutely.  What is the most likely etiologic agent responsible for the lesions shown in this slide?

a.	Multifocal nephritic necrosis
b.	Canine herpes virus
c.	Canine distemper virus
d.	Focal nephritic abscess
e.	Canine parvovirus

54.	Several infant mice in your facility had stunted growth and yellow diarrhea. What is the causative agent?

a.	MHV
b.	Pneumonia virus of mice
c.	Reovirus-3
d.	Tyzzer’s disease
e.	EDIM

55.	What is this specialized technique used to track air movement?

a.	Computational flow analysis
b.	Air movement flow analysis
c.	Computational fluid dynamics
d.	Computed fluid diagnostics
e.	Computational flow diagnostics

56.	An investigator at your facility would like to import this animal.  What is the CITES classification for this animal?

a.	I
b.	II
c.	III
d.	IV
e.	V

57.	What is the OLAW reporting period for animal activity at an institution?

a.  Monthly
b.  Semiannually
c.  Every 36 months
d.  Quarterly
e.  Annually

58.	What does this condition indicate and what is substance secreted?

a.  Fear;  Red Tears
b.  Eustress; Crusts
c.  Distress; Porphyrin
d.  Stress; Porphyrin
e.  Pain; Crusts

59.	What does the acronym depicted in this slide stand for?

a.  Internal Animal Transfer Association
b.  International Animal Transfer Association
c.  International Animal Transfers to America
d.  International Air Transfers to America
e.  International Air Transportation Association

60.	Which anesthetic agent may provide some post-operative analgesia to these rats?

a.  Tribromoethanaol
b.  Ketamine / Xylazine
c.  Pentobarbital
d.  Halothane
e.  Propofol

61.	There are anatomic structures in this species which can create difficulties during intubation.  Which of the following is NOT an anatomic characteristic of this species?

	a.	Long tongue
	b.	Small oral opening
	c.	Hamuli epiglottici
	d.	Palatal ostium

62.	Which of the following restraint methods is considered the least distressful for this species?

	a.	Stanchion
	b.	Restraint sling
	c.	V-trough
	d.	Snout snare

63.	How frequently is this room in a research facility to be inspected by a USDA Veterinary Medical Officer?

	a.	Never
	b.	Semiannually
	c.	Annually
	d.	Triennially

64.	Which of the following drugs has been associated with the clinical disease depicted in this slide?

a.	Metomidate
b.	α-Chloralose
c.	Chloral hydrate
d.	Tiletamine
e.	Methohexital

65.	According to the AVMA Panel on Euthanasia, which of the following is an acceptable method of euthanasia for the animals depicted in this slide?

	a.	Hypothermia
	b.	Nitrogen
	c.	Carbon dioxide
	d.	Barbiturates

66.	If the mean is 12 and the standard deviation is 3, what is the range that accounts for 95% of the values on this plot?

	a.	0 to 25
	b.	9 to 15
	c.	6 to 18
	d.	3 to 21

67.		In this species, what is the purpose of the lateral line (identified by arrow)?

a.	Detection of odor
b.	Detection of water current
c.	Detection of light
d.	Detection of flavor

68.	Which of these diagrams represents a latin square design?

a.	A
b.	B
c.	Neither
d.	Both

69.	The primary function of the equipment depicted in the slide is:

	a.	Non-invasive measure of airway parameters, resistance and conductance
	b.	Chronic intravenous infusion
	c.	Metabolic chamber to measure urine and fecal output.
	d.	Measure blood pressure (indirect)

70.	The purpose of the equipment shown in this slide is to:

a.	 elicit a tactile startle response (stop movement)
b.	 measure foot pad swelling in rodents
c.	 measure body temperature via foot pad
d.	 measure mechanical stimulation and sensory threshold in rodents

71.	What is the schedule assigned to the controlled substance (combination drug) depicted in this slide?

	a.	Schedule I
	b.	Schedule II
	c.	Schedule III
	d.	Schedule IV
	e.	Schedule V

72.	The device depicted in this slide can be used to teach all of the following EXCEPT:

	a.	Intratracheal intubation
	b.	Intraperitoneal injection
	c.	Blood collection
	d.	Intracerebral cannulation

73.	Which of the animals depicted in this slide are covered by the Animal Welfare Regulations?

	a.	Animal A
	b.	Animal B
	c.	Animal C
	d.	Animal D
	e.	All are exempted

74.	All of the following are appropriate endpoint criteria for animals on studies similar to the one depicted in this slide EXCEPT for:

	a.	Weight loss
	b.	Tumor mass
	c.	Presence of ulcer
	d.	Impairment of ambulation

75.	According to the Animal Welfare Regulations, if doing surgery on the animal depicted in this slide, what is required?

	a.	Dedicated surgical suite
	b.	Use of aseptic technique
	c.	Sterile surgeon gown
	d.	Ethanol sterilized instruments

END OF EXAM